Development of a Low Field Overhauser-Enhanced Magnetic Resonance Imaging System
نویسندگان
چکیده
High image contrast in magnetic resonance imaging (MRI) can be achieved by hyperpolarizing the nuclei of interest. Dynamic nuclear polarization (DNP) is a method to create hyperpolarization where excited electron spins induce a larger nuclear spin polarization. Imaging material that has been hyperpolarized by DNP is also known as Overhauser-enhanced magnetic resonance imaging (OMRI). An imager was designed and built to perform OMRI at low magnetic elds around 20mT. The construction of the parts and the whole setup as well as its working principle are reported. Nuclear magnetic resonance (NMR) and MRI have been performed and have proved the operational capability of the setup. DNP was implemented and enhancements of up to 50 in the NMR signal were measured. Overhauser-enhanced imaging was performed to achieve a much better image contrast in comparison to conventional MRI.
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